Chemistry for Dentistry Students

Data

Official data in SubjectManager for the following academic year: 2023-2024

Topic

Medical chemistry includes the topics of general chemistry which are necessary for medical students. It deals also with the chemistry of organic functional groups in concise way. Majority of the curriculum deals with the bioorganic chemistry, which means the chemistry and descriptive biochemistry of biomolecules. The purpose of practices is to study some analytical chemistry and the knowledge of materials. Curriculum of medical chemistry contains the basic knowledge that is necessary to understand biochemistry.

Lectures

• 1. Introduction to Medical Chemistry - Dr. Bognár Zita
• 2. Structure of matter (atoms, ions, molecules, radicals) - Dr. Nagy Veronika
• 3. Intrduction to inorganic chemistry. Oxides, oxoacids, hydroxides, salts - Dr. Nagy Veronika
• 4. Molecular geometry, polarity, molecular interactions - Dr. Nagy Veronika
• 5. Introduction to organic chemistry. Nomenclatute, functional groups, Reaction types - Dr. Nagy Veronika
• 6. States of matter, gas laws. - Dr. Nagy Veronika
• 7. Water and aqueous solutions. Concentration units. Colligative properties of dilute solutions. - Dr. Bóna Ágnes
• 8. Osmosis, composition of biofluids - Dr. Gallyas Ferenc
• 9. Equilibrium, the law of mass action, Le Chatelier principle - Dr. Berente Zoltán
• 10. Role of electrolytes in living organisms, solubilty - Dr. Takátsy Anikó
• 11. Acids and bases, acid-base theories, acid-base reactions - Dr. Takátsy Anikó
• 12. Ion product constant of water, pH, pOH, hydrolysis of salts, pH-dependence of protonation - Dr. Takátsy Anikó
• 13. Buffer solutions - Dr. Takátsy Anikó
• 14. Buffer systems in living organisms - Dr. Takátsy Anikó
• 15. Structure and formation of metal complexes. - Dr. Berente Zoltán
• 16. Metal complexes in living organisms and in medical diagnosis - Dr. Takátsy Anikó
• 17. Thermochemistry - Dr. Berente Zoltán
• 18. Thermodynamics and the direction of chemical reactions - Dr. Takátsy Anikó
• 19. Thermodynamics applied to living systems - Dr. Nagy Veronika
• 20. Reactionkinetics - Dr. Nagy Veronika
• 21. Steady-stateness, a characteristic of living systems - Dr. Nagy Veronika
• 22. Kinetic characteristics of cascade- and cyclic reactions - Dr. Nagy Veronika
• 23. Electrochemistry - Dr. Nagy Veronika
• 24. Electron transfer processes in living organisms - Dr. Berente Zoltán
• 25. Electrochemistry in the medical practice - Dr. Berente Zoltán
• 26. Basics of analytical chemistry for medical students - Dr. Takátsy Anikó
• 27. Basics of separation thechniques for medical students - Dr. Takátsy Anikó
• 28. Analitical instruments in medical diagnostics - Dr. Berente Zoltán
• 29. Reaction types in organic chemistry - Dr. Bognár Zita
• 30. Saturated hydrocarbons: Alkanes. Paraffins in medicine - Dr. Nagy Veronika
• 31. Unsaturated hydrocarbons: Alkenes and alkynes - Dr. Nagy Veronika
• 32. Constitutional, conformational and geometric isomerism - Dr. Nagy Veronika
• 33. Optical isomerism. Relative and absolute configuration. - Dr. Nagy Veronika
• 34. Alcohols, enols, esters (including phosphate and sulphate esters) - Dr. Nagy Veronika
• 35. Phenols, quinones, ethers - Dr. Nagy Veronika
• 36. Aldehydes and their derivatives - Dr. Böddi Katalin
• 37. Carboxylic acids - Dr. Böddi Katalin
• 38. Carboxylic acid derivatives, acylating agents - Dr. Böddi Katalin
• 39. Organic sulfur compounds, thioesters - Dr. Böddi Katalin
• 40. Amines and their biologically significant derivatives - Dr. Balogi Zsolt
• 41. Colloids - Dr. Berente Zoltán
• 42. Colloids found in living systems - Dr. Berente Zoltán

Practices

• 1. Laboratory regulations. Accident and fire protection
• 2. Laboratory regulations. Accident and fire protection
• 3. Solutions, concentration calculation, mass, volume measurement, density.
• 4. Solutions, concentration calculation, mass, volume measurement, density.
• 5. Calculation of active substance concentration on the basis of body weight, preparation of an infusion solution
• 6. Calculation of active substance concentration on the basis of body weight, preparation of an infusion solution
• 7. Disinfectants: experiments with iodine, Lugol's solution. Preparation of an alcoholic solution. Experiment with hydrogen peroxide, preparation of Hyperol solution. Experiments with hypochlorous acid. Sterility at the clinic.
• 8. Disinfectants: experiments with iodine, Lugol's solution. Preparation of an alcoholic solution. Experiment with hydrogen peroxide, preparation of Hyperol solution. Experiments with hypochlorous acid. Sterility at the clinic.
• 9. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
• 10. Experiments with compounds of halogens, oxygen-group and nitrogen group elements
• 11. Experiments with compounds of carbon-group, aluminium and s-block elements
• 12. Experiments with compounds of carbon-group, aluminium and s-block elements
• 13. Potentiometry. Buffer solutions.
• 14. Potentiometry. Buffer solutions.
• 15. Experiments on colloidal systems, chemical equilibria, and catalysis
• 16. Experiments on colloidal systems, chemical equilibria, and catalysis
• 17. Calculations II
• 18. Calculation II
• 19. Experiments in electrochemistry
• 20. Experiments in electrochemistry
• 21. Seminar
• 22. Seminar
• 23. Organic chemistry I. Reactions of functional groups I
• 24. Organic chemistry I. Reactions of functional groups I
• 25. Organic chemistry I. Reactions of functional groups II
• 26. Organic chemistry I. Reactions of functional groups II
• 27. Closing remarks, repetition
• 28. Closing remarks, repetition

Seminars

Reading material

Obligatory literature

P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen

Literature developed by the Department

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Notes

http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Recommended literature

Veronika Nagy (ed.): Laboratory Experiments in Medical Chemistry, Internet edition, Univ. Med. School of Pécs, 2011
Hein-Pattison-Arena-Best: Introduction to Chemistry General, Organic, and Biochemistry, latest edition
P. Gergely (ed.): Organic and Bioorganic Chemistry for Medical Students, latest edition, Univ. Med. School of Debrecen

Conditions for acceptance of the semester

Maximum of 15 % absence allowed

Mid-term exams

Each week's practice scripts include questions that can be found in advance in the workbook. From the 3rd week, students write a small test at the beginning of the practice. Questions will be asked for written answers, with 6 minutes available for the answers. Those who do not take the test during the internship will automatically receive 0 points for this week. With the tests you can get bonus points for the exam. (max. 5 points). The points collected here do not apply to passing the minimum questions, but are added to the final exampoints as extra points. The result of the small test is only valid after the group leader has accepted the protocol booklet. The examination is a colloquium, the questions must be answered and explained in writing. The exam starts with 10 minimum questions.

Making up for missed classes

2 absences are allowed from the 14 occasions of lab and seminar practices.
The semester is not accepted if the student has more than 2 absences. If the student is late more than 5 minutes he/she can not write lab test. If the student is late 5-10 minutes, he/she may perform the lab experiments and this occasion will not be considered as an absence. Less than 5 minutes late is accepted. More than 10 minutes late is absence.
The lab and seminar classes cannot be made up.

Exam topics/questions

The exam is based on the topic of the lectures and labs. It is a written exam, includes 10 MRT questions. Detailed information: http://aok.pte.hu/en/egyseg/oktatasianyagok/20

Examiners

• Andreidesz Kitti
• Dr. Bognár Zita
• Dr. Bóna Ágnes
• Dr. Debreceni Balázs

Instructor / tutor of practices and seminars

• Andreidesz Kitti
• Dr. Balogi Zsolt
• Dr. Bóna Ágnes
• Dr. Jakus Péter Balázs